Scientists have made mice with a remarkable amount of room for human brain tissue to grow.
By genetically engineering animals lacking part of their brain, researchers created a living model in which pea-sized clumps of human neurons could expand, mature and wire into a developing nervous system, ultimately coming to dominate the mouse cortex, the brain’s outer layer.
The model offers a new way to study human neural circuits and brain disease, researchers report September 16 in Nature .
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“Our goal has been to make aspects of human brain development and function accessible for…
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